Double strand break (DSB) repair pathways in plants and their application in genome engineering Bruce Routledge

Double strand break (DSB) repair pathways in plants and their application in genome engineering Bruce RoutledgeIn genome engineering, after targeted induction of double strand breaks (DSBs) researchers take advantage of the organisms own repair mechanisms to induce different kinds of sequence changes into the genome. Therefore, understanding of the underlying mechanisms is essential. This chapter will review in detail the two main pathways of DSB repair in plant cells, non homologous end joining (NHEJ) and homologous recombination (HR) and sum up what we have

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